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Background: Hepatitis C virus (HCV) infection may contribute to the development of diabetes mellitus.
Aim: To examine the prevalence of type 2 diabetes mellitus among adult patients with HCV infection in Aden Yemen.
Materials and Methods: 71 consecutive patients with CHC were prospectively evaluated. CHC infection was defined by the
presence of anti-HCV for at least 6 months. All patients underwent a complete clinical and anthropometric evaluation. The
laboratory evaluation included fasting serum glucose, lipid profile, transaminases and anti-HCV. Categorical variables were
analyzed by the chi-squared and Student?s t-test for continuous variables.P< 0.05 was considered significant.
Results: Among total number of 71 patients of chronic HCV, those who developed type 2 DM were 15 (21%), while among
control group (57 positive to the B markers) were only 5 (8.8%) which statistically significant with p value < 0.05.6 variables were
found significantly related to the 2 DM associated with CHC: male gender, old age, obesity, serum triglycerides, hypertension and
increasing of glucose in blood.
Conclusion: Chronic hepatitis C has many features which suggest that this disease must be viewed not only as a viral disease, but
also as a metabolic liver disease and may contribute to the development of type 2 diabetes mellitus.
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