alexa Prevention Of Diabetic Cataract Pathogenesis Using Olive And Ginkgo Leaf Extracts | 61274
ISSN: 2155-6156

Journal of Diabetes & Metabolism
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

14th International Conference and Exhibition on Targeting Diabetes and Novel Therapeutics

Farid A Badria, Diaaeldin M Elimam and Ahmed S Ibrahim
Mansoura University, Egypt
Posters & Accepted Abstracts: J Diabetes Metab
DOI: 10.4172/2155-6156.C1.058
Abstract
The most common secondary diabetic complication is cataract, the opacity of the lens that produces painless gradual loss of vision. Diabetic cataract is usually acquired during persistence hyperglycemia through increasing the glucose level greatly in eye lens where glucose entry is independent of insulin. This excess glucose is metabolized via an accessory pathway known as the polyol pathway. Activation of this pathway leads to the accumulation of the osmolyte sorbitol in eye lens resulting in osmotic swelling and subsequent hydropic lens fibers that degenerate to form sugar cataracts.A number of structurally diverse compounds inhibit aldose reductase significantly; many of these compounds possess poor pharmacokinetic properties or side-effects not associated with the specific inhibition of aldose reductase. These problems reflect a need for the development of new, more effective and safe drug which may raise the therapeutic benefits for diabetic patients. Therefore, a renewed interest in use of plant-based medicine in the area of health care has been promoted. Olive leaf extract (OLE) as well as Ginkgo leaf extract (GLE) are natural supplements that have wide therapeutic indices with very low toxicity. The present study sought to evaluate the biochemical effectiveness of OLE and GLE on cataract formation during hyperglycemia and to gain insight into the inhibition mechanism involved therein.
Biography

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7