Prognostic factors for surgical outcome and survival in women treated for borderline ovarian tumors

Joint Event on 28^th International Conference on Cancer Research and Anticancer Therapies & International Conference on Oncogenesis & Oncologic Emergency Medicine & 3^rd International Conference on Tumor & Cancer Immunology and I

September 17-18, 2018 | San Diego, USA

Medhat Esam Eldin Helmy, Gamal Amira, Amany Abd-Elhameed Abou-Bakr, Nabih Elsebaey Elkhouly, Haitham Aboali Hamza and MohamedZakaria Sayer Dayer

Menoufia University, Egypt
Cairo University, Egypt

Scientific Tracks Abstracts: J Cancer Sci Ther

Abstract :

Data of 92 patients diagnosed with borderline ovarian tumors (BOTs) during the period from 2010 to 2017 in the National Cancer Institute (NCI), Cairo University, Egypt were retrospectively evaluated, Median follow up period was 42 months. The mean age at diagnosis was 42.7 yrs. Histopathology was serious in 63%, mucinous in 28.3%, and endometrioid in 3.3%. 65 patients (70.7%) had Stage IA disease, 17 patients had Stage IB disease (18.5%), 4 patients had Stage IC disease (4.3%), 2 patients had Stage II disease (2.2%) and 4 patients had Stage III disease (4.3%) at diagnosis. 49 patients (53.3%) underwent fertility-sparing surgery, of which 19 patients underwent Unilateral ovarian cystectomy, 5 patients underwent Bilateral ovarian cystectomy, 25 underwent Unilateral salpingo-oophorectomy. 43 patients (46.7%) underwent radical surgery including hysterectomy, bilateral salpingo-oophorectomy. 39 patients had micropapillary disease (42 %) and 2 patients had microinvasive disease (2.2%) on histopathology. 6 patients (6.5 %) had peritoneal implants of which 1 was invasive and 5 were non-invasive. The recurrence rate in the entire study group was 18.5%, 17.6% among patients underwent radical surgery and 82.4% among patients underwent fertility-sparing surgery. 12 of the recurrences (70.6%) were borderline whereas 5 were invasive (29.4%). Stages IA and IB had significantly higher disease-free survival than other stages. Patients with micro invasion had significantly lower free disease-free survival 10.5(9.52â??11.5) vs 77.6(70.9 â?? 84.1). Radical surgery had significantly higher FDS than fertilitysparing surgery 75.8(70.2 â?? 81.4) vs 68.5(58.2 â?? 78.8).

Biography :

Mohamed Zakaria is currently working as a Assistant Lecturer of Gynecology & Obstetrics at Menoufia University. His Research Interest includes Ovarian tumors.

E-mail: mimo_zsd@yahoo.com