alexa Proliferation Inhibitory Effects Of Peppermint Oil On Human Breast Cancer Cell Lines
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

4th World Congress on Cancer Science & Therapy
October 20-22, 2014 DoubleTree by Hilton Hotel Chicago-North Shore Conference Center, USA

Seyedeh Zeinab Taheri Rouhi
Posters: J Cancer Sci Ther
DOI: 10.4172/1948-5956.S1.034
Abstract
Background: Essential oils and their exclusive scent ingredients showed cancer preventive activity when examined on various human cancer cell lines containing human liver tumor, pulmonary tumors, colon cancer, gastric cancer, breast cancer, leukemia and others. Objectives: The goal of this trial was to determine the anti-proliferation activity of peppermint essential oil on the induction of apoptosis (programmed cell death) and cell cycle advancement in human breast carcinoma cells. Methodology: Human breast carcinoma cells (estrogen receptor (ER)-positive (MCF-7) and -negative (MDA-MB-231) were used. Apoptosis was assessed byMTT assay and Propidium iodide (PI) and Hoechst 33342 staining. The migration of cancer cells were assessed using scratch assay. The genes involved in cell cycle control and apoptosis were evaluated utilizing Real Time PCR. Results: The results showed that essential oils from peppermint inhibited the growth of both MCF-7 and MDA-MB231 at 350 and 550 μg/ml. Apoptotic cells were observed when the treated cells were stained with propidium iodide and Hoechst 33342 under fluorescence microscope. An up-regulation of apoptotic genes p53 and Bid as well as elevation of Bax/Bcl2 ratio was observed. Conclusion: The results concludes that peppermint oil may protect against breast cancer by leading to cell cycle arrest and inducing apoptosis. It requires to be appraised in human trials.
Biography
Seyedeh Zeinab Taheri Rouhi is presently a Research Assistant in the Department of Molecular Medicine, University Malaya. She is currently pursuing her last semester in master of nutritional science at the University of Putra Malaysia, waiting for her viva examination. She has 3 papers under process. She is interested in doing research in diabetes type 2, cancer and obesity areas.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords