alexa Protective Effects Of Tunisian Medicinal Plant Salvia Officinalis On Cytotoxicity, And Histological Changes In Vanadium-induced Renal Toxicity In Rats | OMICS International
ISSN: 2161-0959

Journal of Nephrology & Therapeutics
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading Please wait..

11th International Conference on Nephrology & Urology
March 22-23, 2017 Rome, Italy

Fatma Ghorbel Koubaa, Ahlem Soussi Ben Salah, Mouna Turki, Fatma Makni Ayadi, Mohamed Dammak, Raed Abdennabi, Lassaad Belbhri and Abdelfattah El Feki
University of Sfax, Tunisia
Dammak Pharmacy, Sfax. Tunisia
Laboratory of Pharmacognosy and Natural Products Chemistry Athens 15771, Greece
University of Neuchatel, Switzerland
NextBiotech, 98 Rue Ali Belhouane, 3030 Agareb, Tunisia
Posters & Accepted Abstracts: J Nephrol Ther
DOI: 10.4172/2161-0959.C1.037
Aim: In recent years, there has been an increased interest in vanadium (V) because of its toxicological effects and pro-neoplastic action that affects many organs, specially the kidney. Aim of this study was to evaluate protective effect of medicinal plant on vanadiuminduced renal toxicity in adult male Wistar rats. Methodology: The animals were divided into three groups of six animals each: Group C served as control which received oral gavage with NaCl 0.9%; group V received oral gavage with NaCl 0.9% and injected by vanadium; group SV received oral gavage with essential oil of Salvia officinalis and injected by vanadium for 10 days. Results: Administration of vanadium intraperitoneally for 10 days increased significantly (p<0.05) the levels of serum renal markers [creatinine, urea, blood urea nitrogen (BNU), lactate dehydrogenase (LDH), alkaline phosphatase (ALP) activities and lipid peroxidation thiobarbituric acid reactive substances (TBARS) and protein carbonyl]. Co-administration of the plant essential oil shows a decrease of the tested parameters and an increase of the endogenous antioxidants levels. The vanadium-induced histopathological changes were also minimized with the tested extract. Conclusion: These results suggest that the essential oil of Salvia officinalis might play a role in reducing the toxic effect of vanadium and its biochemical parameters seem to mediate such a protective effect.


image PDF   |   image HTML

Relevant Topics

OMICS International Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version