alexa Reinventing The Gene Vaccine: Non-viral Delivery Of MRNA
ISSN: 2155-9899

Journal of Clinical & Cellular Immunology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

3rd International Conference and Exhibition on Clinical & Cellular Immunology
September 29-October 01, 2014 DoubleTree by Hilton Baltimore-BWI Airport, USA

Sylvie Bertholet
ScientificTracks Abstracts: J Clin Cell Immunol
DOI: 10.4172/2155-9899.S1.017
Abstract
Novartis has developed the SAM?vaccine platform. This platform, now in pre-clinical development, is based on a synthetic, self-amplifying mRNA, delivered by a synthetic lipid nanoparticle (LNP). The broad utility of this novel vaccine technology has been demonstrated with genes encoding vaccine candidate antigens from several pathogens and was found to elicit broad and potent protective immune responses in multiple animal models. Immune responses are comparable to a viral technology, but without the inherent limitations of viral vectors. Furthermore, the recent combination of rapid and accurate cell-free gene synthesis and SAM vaccine technology allowed the generation of a pandemic H7N9 vaccine candidate in one week from posting of the gene sequence on the CDC website. If the SAM vaccine platform proves safe and effective in humans, fully synthetic vaccine technologies could provide unparalleled speed of response to stem the initial wave of outbreaks, with a vaccine candidate ready days after the discovery of a new virus.
Biography
Sylvie Bertholet is currently head of In Vivo Immunology at Novartis Vaccines & Diagnostics (NVD) Italy, responsible for the immunological characterization of next generation Staphylococcus aureus and influenza vaccines. She has over 20 years of experience in infectious diseases and vaccine development. She received her PhD in Immunology from the University of Lausanne, Switzerland, and completed her Postdoctoral training at the University of Lausanne and at the National Institutes of Health in Bethesda, studying host-pathogen interactions. Prior to joining NVD, she held position at the Infectious Disease Research Institute in Seattle leading Tuberculosis, Pneumococcus and Leishmania vaccine development projects. She has authored more than 40 publications on infectious disease and vaccine-related topics.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords