Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
This lecture will address topics related to the search for potential biomarkers for cervical cancer. The first part of this lecture
will present the prevalence of cervical cancer on a worldwide scale; the interplay between high-risk HPV and host cell
molecules in cervical cancer development; and the need for robust biomarkers. In the second part, the topics will focus on
critical parameters to achieve reliable qPCR results in obtaining mRNA and miRNA markers for cervical cancinogenesis;
and will include discussions on: The careful evaluation of expression stability of candidate reference genes; the importance of
including cervical premalignant lesions in gene stability analyzes; the use of individual samples x pool of samples; the use of
multiple reference genes; the use of a single reference gene. Therefore, attendees of this lecture will be familiarized with the
needs for rigorous validation of reference genes in qPCR assays to identify reliable biomarkers for cervical carcinogenesis.
Eliane Campos Coimbra is a Biologist with Master in Genetics (2007) and PhD in Therapeutic Innovation (2012) at Federal University of Pernambuco. Currently
she is Postdoctoral research fellow of the Laboratory of Molecular Studies and Experimental Therapy (LEMTE) at Department of Genetics, Federal University of
Pernambuco. Her research focuses on HPV infection and cervical cancer, including the development of vaccinal strategies and evaluation of mRNA and microRNA
expression changes, to understanding the molecular basis of cervical carcinogenesis and to identify potential biomarkers.
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals