alexa Shaping The Microenvironment For Physiological Cultivation Of Human Adult Stem Cells
ISSN: 2157-7552

Journal of Tissue Science & Engineering
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

3rd International Conference on Tissue Science & Regenerative Medicine
September 24-26, 2014 Valencia Convention Centre, Spain

Cornelia Kasper, Verena Charwat, Anne Neumann, Maike Keck and Peter Ert
ScientificTracks Abstracts: J Tissue Sci Eng
DOI: 10.4172/2157-7552.S1.014
Abstract
A lthough our knowledge about the in vivo microenvironment of stem cells (the biological niche) is steadily increasing, ?standard? cell cultivation is still performed under not physiologically relevant conditions. Usually cells are cultivated under ambient oxygen conditions in static 2D cultures on plastic surfaces. Since cellular responses are highly dependent on the complex interplay between cells and their microenvironment, it is important to develop more physiologically relevant cultivation systems for in vitro cellular studies. For specialized stem cell cultivation already several bioreactor systems are available. These systems have the advantage that they provide medium perfusion which enables better oxygen and pH control as well as continuous nutrient supply and waste removal. Furthermore dynamic cultivation allows mechanical stimulation, which is an important cue for stem cell differentiation. A great variety of specialized bioreactors ranging from miniaturized to large-scale systems on 2D surfaces and within 3D tissue-like matrices with and without integrated biosensors has been developed. The lecture will provide an insight into dynamic cultivation of human adult stem cells in specialized bioreactor systems. A general introduction will be focused on the unique characteristics of dynamic stem cell cultivation and the differences to standard cultivation procedures. The potential and benefits of dynamic cultivation will be highlighted, but also risks, potential pitfalls and limitations of will be discussed. Different dynamic systems for stem cells expansion and differentiation will be introduced. The presented bioreactor types will range from miniaturized microfluidic set ups to clinical scale reactors and include 2D cultures as well as 3D tissue-like structures.
Biography
Cornelia Kasper completed her PhD in 1998 from Leibniz University of Hannover (Germany) and her habilitation in 2007 at the Institute for Technical Chemistry at the Leibniz University of Hannover. She was appointed as full University Professor for ?Biopharmaceutical Production and Technology? at University of Natural Resources and Life Science (BOKU) in Vienna (Austria) at the Department of Biotechnology. She has published more than 80 papers in reputed journals and several book chapters and is editor within the series ?Advances in Biochemical Engineering and Biotechnology? (Springer) of several volumes covering actual areas in Tissue Engineering and Stem Cell Research. She is also reviewer for many distinguished journal within the field of biotechnology/bioprocess and bioreactor design and enablelingtechnolgies for stem cell cultivation
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version