Should Complementary Therapies Be Used To Lowering Blood Pressure In Adult Hypertensive? A GRADE Of Quality Of Evidence And Strength Of Recommendations | 50279
Journal of Clinical & Experimental Cardiology
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Obejctive: The purpose of this work is using GRADE approach to rate the quality of evidence in systematic reviews which examined
complementary therapies efficacy and safety for lowering blood pressure and evaluating the strength of recommendation in order to
determine that should complementary therapies be used to lower blood pressure in adult hypertensive.
Method: Six electronic databases and the reference lists were searched for eligible systematic reviews. Characteristics of included
reviews, results of meta-analysis, assessment of methodological quality and risk of bias of studies were collected and AMSTAR score
were used for rating the methodological quality of included systematic reviews. GRADE approach was used for grading the quality
of evidence and strength of recommendations. Evidence used to evaluate the strength of recommendation were only collected from
comparisons between complementary therapies and antihypertensive drugs.
Results: Nine interventions were included in the qualitative synthesis. Quality of evidence in all included systematic reviews was
assessed, and they were generally not high. Only systematic reviews of Qigong, massage and acupuncture were used to make
recommendation. The rigorous assessment resulted in a high recommendation pertaining to Qigong and a weak recommendation to
massage, whether they were used alone or in combination with other therapies. Acupuncture used alone was recommended to only
use in research and used in coordination with antihypertensive drug was given a weak recommendation
Conclusion: We thought that Qigong could be used to lower blood pressure in clinic, but massage and acupuncture plus antihypertensive
drug should be used with caution.