alexa Sigumjang Meju (fermented Barley Bran) Water-soluble Extracts Attenuate Gastro Mucosal Injury And Inflammatory Responses-induced By Acute Alcohol Intake In Vivo
ISSN 2472-0542

Journal of Experimental Food Chemistry
Open Access

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2nd International Conference on Food Chemistry & Nutrition
July 24-26, 2017 Vancouver, Canada

Sumin Ha, Hojeong Jeong, Ginyung Jeong, Geutae Kim1and Gi Dong Han
1Department of Food Science and Technology, Yeungnam University, Gyeongsan, Republic of Korea
Posters & Accepted Abstracts: J Exp Food Chem
DOI: 10.4172/2472-0542-C1-009
Abstract
Acute alcohol intake causes multiple organ damages such as severe acute gastrointestinal, liver and cardiovascular diseases. In present study, the gastro protective effects of sigumjang meju (fermented barley bran) water extract (SME) on experimental model of ethanol (EtOH)-induced gastric ulcer in mice. The gastro protective activity of SME was evaluated by gross/histopathological inspection, pro-inflammatory cytokine, and EtOH absorption from stomach. SME pretreatment is characterized to less gastrointestinal bleeding and reduced EtOH absorption into the bloodstream via gastro mucosal barrier. Furthermore, the SME effectively reduced the expression of pro-inflammatory mediator of TNF induced by EtOH. These results indicate that SME prevents gastric mucosal damage induced by acute EtOH administration in mice through the protective effects of SME for anti-inflammatory activities and less absorption of EtOH from stomach.
Biography

Ha Sumin is working at the Department of Food Science and Technology, Yeungnam University, Gyeongsan, Republic of Korea.

Email: [email protected]

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