Stable biocompatible silver nanoparticles (w/o) cream for safe, better and empiric wound healing

2^nd International Conference and Exhibition on Pharmaceutical Regulatory Affairs

November 23-24, 2012 Hyderabad International Convention Centre, India

Alekhya. Sanaboina and Vineela. Ramavath

Accepted Abstracts: Pharmaceut Reg Affairs

Abstract :

Wound healing is an intricate process of classic model containing three to four sequential, overlapping phases begins at injury onset. It is a complex process and has been the subject of intense research for a long time. The recent emergence of nanotechnology has provided a new therapeutic modality in silver nanoparticles for use in burn wounds. Nonetheless, the beneficial effects of silver nanoparticles on wound healing remain unknown. We investigated the wound healing properties of silver Nanoparticles in an animal model and found that rapid healing and improved cosmetic appearance occur in a biocompatible, bio functionalized and dose dependent manner. As it is known that silver acts by producing lethal effect on resistant bacterial strains, in this paper we highlight on the effect of biocompatible silver nanoparticles efficacy in producing its wound healing effects. Furthermore we showed that silver nanoparticles exert positive effects through their antimicrobial properties, reduction in wound inflammation and modulation of fibro genic cytokines. These results have given insight into the actions of the silver and have provided a therapeutic direction for wound treatment in clinical practice.

Biography :

Alekhya anaboina and Vineela.Ramavath, pursuing Pharm D fifth year in H.K.E.Society?s Matoshree Tara Devi Rampure Institute of Pharmaceutical Sciences, Gulbarga. The research work is done under the supervision of Dr.Raghunandan Deshpande, Professor In charge and HOD, department of Pharmaceutical and Nanochemistry, HKES MTRIPS, Gulbarga.