Journal of Nutrition & Food Sciences
Open Access

Statistical analysis for the gut microbiome-diet association: An overview

3^rd International Conference and Exhibition on Nutrition & Food Sciences

September 23-25, 2014 Valencia Convention Centre, Spain

Mihaela Pricop-Jeckstadt

Scientific Tracks Abstracts: J Nutr Food Sci

Abstract :

In this talk we present several statistical approaches applied until now in the study ofthe gut microbiome-diet association and deploy them to analyze the PopGen cohort (see(1)). Taxa abundances and phylogenetic tree deduced out of the microbial metagenomicsdata are used to characterize the microbiome diversity, while nutritional data consists of thehabitual dietary intake. High-dimensionality, sparsity, heterogeneity and dependency of thedata enforces the use of the regularization methods to identify taxon-diet intake associations(see (2)). On the other hand, food pattern-gut microbial enterotype relationship could beidenti_ed with the help of ordination and classification methods (see (3), (4)). Finally, thesestatistical methods serve to detect microbiome-food intake connections after taking in con-sideration di_erent lifestyle and demographics data from the PopGen cohort.