Subclavian Artery Stenosis/thrombosis In A Post CABG Patient While Undergoing Dialysis For CKD Using Left AV Fistula, Presenting As ST Elevation Myocardial Infarction And Acute Limb Ischemia (Double Trouble - Advanced Coronary Blood Flow Diversion: A Coronary Subclavian Steal Syndrome) | 58449
Journal of Clinical & Experimental Cardiology
Like us on:
Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Subclavian artery stenosis/thrombosis in a post CABG patient while undergoing dialysis for CKD using left AV fistula, presenting as ST elevation myocardial infarction and acute limb ischemia (Double trouble - Advanced coronary blood flow diversion: A coronary subclavian steal syndrome)
13th European Cardiology Conference
Ryan D Andal, Jasmin Melissa Bernardo and Joaquin Jison
Background: Coronary subclavian steal syndrome is a rare disorder, mostly unrecognized and under diagnosed , seen in patients
developing subclavian artery stenosis after Coronary Artery Bypass Graft using the LIMA –LAD graft diverting blood flow from
the native coronary LAD back to the graft LIMA –LAD into the subclavian artery in a retrograde fashion. This disorder causes
significant symptoms which is brought about by ischemia coming from the heart, left upper extremity and the brain which was
worsened by the ongoing dialysis.
Case Presentation: We describe a case of a 58-year-old male, with history of diabetes mellitus, hypertension, post CABG using LIMALAD
graft and Mitral valve replacement 6 years ago,who developed Chronic Kidney Disease (CKD) requiring dialysis 3x a week using
AV fistula left arm. 1 week prior, he developed grade 3-4/10 chest heaviness, dull in character with associated headache and left arm
pain while having dialysis. Hemodialysis (HD) blood flow rate was reduced to decrease the symptoms. Until 30 minutes post HD
now with severe intensity 10/10 chest pain radiating to left shoulder with associated left hand numbness/weakness , headache and
shortness of breath.
Computed Tomography of the chest with contrast incidentally showed a short segment thrombus in the proximal left subclavian
artery at its origin from the aortic arch, resulting in severe luminal stenosis or near total occlusion.
Left heart catheterization with coronary angiography,selective angiogram of the left subclavian and right brachiocephalic artery
showed the presence of a 90-95 percent occlusion at the proximal subclavian artery most probably due to a calcific plaque and
or thrombus. Attempt was made to pass the guidewire through the occlusion but was unsuccessful. Since the lesion could not be
percutaneously reperfused, decision to proceed to catheter directed thrombolysis was made with plans for surgery afterwards. A
catheter directed streptokinase 250,000 IU was injected over 30 mins.
Repeat selective angiography of the SA showed calcified left subclavian artery with 10% narrowing at the base with good arterial flow
all the way to the left brachial artery. The vertebral artery and LIMA-LAD grafts were patent.
Conclusion: While the use of a LIMA graft with CABG has become widely accepted as the standard of care, left subclavian artery
stenosis can compromise anterograde blood flow in the LIMA and if severe, can result in coronary subclavian steal syndrome . It is
suggested that if there is a post CABG patient on dialysis, the presence of a supraclavicular bruit and an interarm BP difference of at
least 20 mmhg should be routinely done prior to dialysis detect early SA stenosis , especially if during dialysis they have symptoms
of chest pain , vertebrobasilar insufficiency and limb ischemia would be valuable. Close follow-up of such patients is of utmost
importance, as any future recurrent symptoms could be fatal due to the underlying functionally impaired conduit. Attention should
be placed in considering site of HD access in post valve repair and post CABG requiring dialysis , and if possible to perform also
subclavian angiography whenever a post CABG patient on HD undergoes coronary angiogram.
Ryan D. Andal has completed his College at the age of 18 years from De La Salle University Manila with a degree in Medical Physics and postdoctoral studies from University of Santo Tomas , Manila. He trained in internal medicine at the Makati Medical Center and his 3rd year of fellowship in cardiology. He is board certified in Internal Medicine and plans to pursue interventional cardiology after his fellowship training.