alexa Synbiotic Effects Of β-glucans From Cauliflower Mushroom And L. Fermentum On Menopausal Symptoms And Gut Microbiome In Estrogen-deficient Rats
ISSN: 2329-6836

Natural Products Chemistry & Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

2nd International Conference and Exhibition on Marine Drugs and Natural Products
June 15-17, 2017 London, UK

James W Daily
Daily Manufacturing Inc., USA
Keynote: Nat Prod Chem Res
DOI: 10.4172/2329-6836-C1-012
Abstract
Since gut microbiota influences obesity and bone mineral density, probiotics, prebiotics and synbiotics may attenuate menopausal symptoms by modulating gut microbiota in estrogen-deficient animals. We investigated whether the longterm consumption of L. fermentum (probiotics) and cauliflower mushroom (prebiotics) would prevent and/or delay the progression of post-menopausal symptoms in estrogen-deficient Ovariectomized (OVX) rats with diet-induced obesity and explored their mechanisms of action. OVX rats were fed with high fat diets containing 1% dextrin (control), 1% lyophilized cauliflower mushroom plus 0.1% casein (CFM), 0.1% L. fermentum plus 1% dextrin (LFE), 1% CFM plus 0.1% LFE (CFLF), or 30 μg/kg body weight 17β-estradiol plus 1% dextrin (positive-control). CFM mainly contained β-glucans (about 95.8%). OVX exhibited impaired energy, glucose and lipid metabolisms and changed gut microbiome, and 17β-estradiol treatment prevented the impairment. Only CFLF lowered tail skin temperature without increasing serum 17β-estradiol and uterine index. CFLF and positive-control groups increased daily energy expenditure and fat oxidation. Dyslipidemia induced by OVX was improved by CFM and CFLF and CFLF prevented the dyslipidemia as much as in the positive-control group. Serum glucose levels and insulin levels were lower in CFLF as much as in the positive-control group. HOMA-IR was rather lower in CFLF than in the positive-control. Hepatic insulin signaling (pAkt→GSK-3β) was also potentiated in the ascending order of the control, LFE, CFM, CFLF, and positive-control. AMPK phosphorylation showed similar patterns of hepatic insulin signaling but LFE increased it more than CFM. OVX increased the ratio of Firmicutes and Bacteroidetes and decreased the ratio of Actinobacteria plus Proteobacteria in the large intestines. The changes were prevented by CFLF as similar to the positivecontrol group. In conclusion, OVX changes gut microbiota and the changes were associated with menopausal symptoms and synbiotics of CFM and LFE prevented the gut microbiota and menopausal symptoms in estrogen-deficient animals.
Biography

James Daily has his expertise in Medicinal Plants and Natural Products from different sources, James Completed his PhD at the University of Tennessi. Currently he is working has a CEO at Daily Manufacturing Inc. USA. He has published number of papers in reputed journals and has been serving as an associate editor of J Medicinal Food.

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords