alexa Synthesis And Characterization Of 2-((4R,4aR,5aS,6S)-1,3-dioxo3m3a,4,4a,5,5a6,6a-octahydro-4,6- Ethenocyclopropa[f]isoindol-2(1H)-yl)-N-(substituted Phenyl) Acetamides Anticipated To Have HIV- 1 Activity | 66622
ISSN: 2161-0444

Medicinal Chemistry
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6th World Congress on Medicinal Chemistry and Drug Design
June 07-08, 2017 Milan, Italy

Abdulmajeed S H AlSamarrai and Noor H Abdulla
Department of Chemistry, University of Samarra, Iraq
ScientificTracks Abstracts: Med Chem (Los Angeles)
DOI: 10.4172/2161-0444-C1-030
Abstract
This work includes the synthesis of some new 2-((4R,4aR,5aS,6S)-1,3-dioxo3,3a,4,4a,5,5a6,6a-octahydro-4,6-ethenocyclopropa[f] isoindol-2(1H)-yl)-N-(substituted phenyl) acetamides (3-11) by reaction of (4R,4aR,5aS,6S)-1,3-dioxo 3,3a,4,4a,5,5a,6,6aoctahydro- 4,6-ethenocyclopropa[f]isoindole-1,3-(2H,3aH)-dione (1) with 2-chloro-N-(substituted phenyl) acetamides (2) in the presences of potassium carbonate in refluxing acetonitrile as a solvent. These compounds have been identified by spectroscopic methods including, IR, 1H-NMR, 13C-NMR and elemental analysis (CHN).
Biography

Abdulmajeed S H AlSamarrai was awarded a BSc in chemistry by the Mosul University of Iraq and MSc in analytical chemistry , by Baghdad University of Iraq and was awarded a PhD in organic chemistry by university of Birmingham/ UK in 1984. He is an assistant professor, department of chemistry, Tikrit university , Iraq (1991-2001). Then since 2001, he is a faculty member in the department of chemistry at the University of Samarra, Iraq and he is working as a professor of organic chemistry. Dr. ALSamarrai research interests are on organic synthesis of heterocyclic compounds and has published about 30 papers in reputed journals.

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