Modern Chemistry & Applications

Synthesis of sulfonamide compounds bearing thiazole ring

International Conference on Applied Chemistry

October 17-18, 2016 Houston, USA

Mustafa Arslan and Soner Kilicaslan

Sakarya University, Turkey

Posters & Accepted Abstracts: Mod Chem appl

Abstract:

Heterocyclic moieties, such as indoles, thiazolidine-4-ones, pyrazoles, piperazines, pyridines, etc., always have considerable attention due to their pharmacological activities. Heterocycles bearing one or more nitrogen and sulfur atoms have received more attention recently. Among the most frequently encountered heterocyclic compounds, thiazole and its derivatives play an important role in nature. The heterocyclic compounds have broad applications including the treatment of hypertension, bacterial and HIV infections, allergies and as antibiotics and ligands for estrogen receptors. Besides, these compounds have used as inhibitors against fructose 1, 6-bisphosphatase, tumor associated carbonic anhydrase isoforms hCA IX and hCA XII, sphingosine kinase and evaluation of in vitro anticancer activity. 12 sulfonamide bearing thiazole compounds were synthesized for the investigation of carbonic anhydrase enzyme activity.

Biography :

Mustafa Arslan has completed his PhD from Cleveland State University. He has been working at the Sakarya University, Chemistry Department as an academic staff since 1998. He has attended more than 35 national and international conferences. He has published more than 40 papers in reputed journals and his publications have been cited more than 400.

Email: marslan@sakarya.edu.tr