alexa Systemic Erythematosus Lupus (SLE) Associated With A Positive PR3-ANCA: A Case Report | 61491
ISSN: 2161-0959

Journal of Nephrology & Therapeutics
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

10th European Nephrology Conference
October 24-26, 2016 Rome, Italy

Y Lounici, A Hassan, D Khelifi Touhami, I Berkane and M Bouali Benhalima
Mustapha Bacha Teaching Hospital, Algeria
Posters & Accepted Abstracts: J Nephrol Ther
DOI: 10.4172/2161-0959.C1.034
Abstract
The objective of this work is to report and discuss the case of a patient who fulfilled the criteria for Systemic erythematosus lupus (SLE) and presented high rates of anti-proteinase 3 antibodies (anti-PR3). We report the case of a 68-year-old man who presented at the onset of the disease an important asthenia and a significant loss of weight (more than 10 kg in few months). He consulted for a sudden and severe dyspnea, chest pain and a fever. The clinical examination done by his doctor revealed a pleural effusion and an edema of his legs. Few weeks later, new symptoms appeared: Abdominal pain, arthralgias and proteinuria. An inflammatory syndrome was noticed at diagnosis with a high rate of CRP (CRP=96). Concerning the immunological tests, a very high titer of ANA (homogenous 1/1000) with positive anti-DNAn antibodies on crithidia luciliae was found. This patient had also a cytoplasmic- ANCA (c-ANCA) with a titer of 1/80 and his anti-PR3 antibodies were at a rate of 132 U/ml (Normal value<20 U/ml). Few cases of associations between SLE and AAV were reported in the literature and all of them had MPO-ANCAs. To the best of our knowledge, to date there have been no case reports of AAV with positive anti-PR3 antibodies in patients with SLE. The diagnosis of AAV in the setting of SLE is a real challenge and it’s crucial to establish it in order to choose the best treatment approach.
Biography

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version