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The Association Between Carbon And Nitrogen Stable Isotope Ratios Of Human Hair And Cardiovascular Risk Factors | 43859
ISSN: 2153-0769

Metabolomics:Open Access
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The association between carbon and nitrogen stable isotope ratios of human hair and cardiovascular risk factors

5th International Conference and Exhibition on Metabolomics

Song Vogue Ahn

Yonsei University, Korea

Posters & Accepted Abstracts: Metabolomics

DOI: 10.4172/2153-0769.C1.032

It has been reported that stable isotopic ratios can be used as biomarkers for animal protein intake. A high protein or meat intake could be a risk factor for metabolic disorders. We investigated whether the carbon or nitrogen stable isotopic ratio of human hair is associated with cardiovascular risk factors. We conducted a cross-sectional study within the Korean Genomic Rural Cohort Study in 2011. Hair samples from 399 subjects (233 men and 166 women) aged 40 and over were measured for carbon [δ13C={(13C/12C) sample/(13C/12C)Pee dee Belemnite}-1] and nitrogen [δ15N={(15N/14N)sample/(15N/14N)Air}-1] stable isotopic ratios. Cardiovascular risk factors, including anthropometrics, blood pressure, serum adiponectin, leptin, gamma-glutamyltransferase were measured. Men showed a negative correlation between δ15N and serum adiponectin, a positive correlation between δ15N and serum leptin. Women showed a positive correlation between δ15N and serum leptin. On multivariable models, δ15N was negatively associated with serum adiponectin in men and positiveely associated with serum leptin in women. The δ15N value of human hair might be a surrogate marker associated with cardiovascular risk factors.

Song Vogue Ahn has completed his MD and PhD from Yonsei University. He is working as an Associate Professor at the Department of Preventive Medicine, Yonsei University Wonju College of Medicine and Director of the Institute of Genomic Cohort, Yonsei University. He has published more than 35 papers in reputed journals and has been serving as an Editorial Board Member of the repute.

Email: [email protected]