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The effects of electropulsing induced gradient topographic oxide coating of Ti-Al-V alloy matrix strips on the fibroblast
adhesion and growth were investigated. The goal in biomaterial surface modification was to possess desired recognition
and specificity through modifying its surface condition like topological structure. Here we developed a unique strategy of highenergy
electropulsing treatment (EPT) for manipulating surface gradient bio-functionalization of basal textured Ti-6Al-4V
alloy strips with the surface gradient topographic oxide coating, which brings in the gradient distribution of surface conditions
including matrix alloy, ordinary TiO2 film and TiO2 microwaves on a single strip. High-energy electropulse is frequently used
as an electrically-treated method in improving the material microstructure and mechanical property. The current investigation
reports firstly the surface modification under EPT aiming to improve the biocompatibility, which will meet the demand of
biomaterials in different parts of human beings. Novel TiO2 microwave topological structure on the material surface resulted in
better biocompatibility with more active fibroblast bio-reaction including higher cell viability, better physiological morphology
and stronger adhesion binding, which is ascribed to surface chemical components, surface energy and specific surface area
under EPT manipulation. Thus, the gradient functionalization of biomaterials formed within seconds under EPT in the
titanium alloys could open an energy-saving and high-efficiency door to diverse biomedical applications including the tissue
engineering and biological interfaces.
Guoyi Tang is Professor of Materials Science, Advanced Materials Institute of Graduate School at Shenzhen, Tsinghua University, where he teaches courses in materials science frontier and engineering materials: performance, selection and design. He accumulated years of research experience when working as a visiting Professor in Stuttgart University and Max-Planck Institute, Germany, University of Alaska Fairbanks and North Carolina State University, USA, and Nanyang Technology University, Singapore. His recent research interests focus on electroplastic processing technology, phase change materials, biomass and bio-degradable polymer composites, and etc. He has published more than 120 scientific papers and obtained 35 Chinese patents.