alexa The Effect Of Platelet Rich Plasma (PRP) In The Hair Re-growth: A Randomized Placebo-controlled Trial
ISSN: 2155-9554

Journal of Clinical & Experimental Dermatology Research
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

5th International Conference and Expo on Cosmetology, Trichology & Aesthetic Practices
April 25-27, 2016 Dubai, UAE

Pietro Gentile
University of Rome “Tor Vergata”, Italy
ScientificTracks Abstracts: J Clin Exp Dermatol Res
DOI: 10.4172/2155-9554.C1.026
Abstract
Platelet-rich plasma (PRP) has emerged as a new treatment modality in regenerative plastic surgery, and preliminary evidence suggests that it might have a beneficial role in hair re-growth. Here, we report the results of a randomized, evaluator-blinded and placebo-controlled, half-head group study to compare, with the aid of computerized trichograms, hair re-growth with PRP versus placebo. The safety and clinical efficacy of autologous PRP injections for pattern hair loss were investigated. PRP, prepared from a small volume of blood was injected on half of the selected patients’ scalps with pattern hair loss. The other half was treated with placebo. Three treatments were administered to each patient at 30-day intervals. The endpoints were hair re-growth, hair dystrophy as measured by dermoscopy, burning or itching sensation and cell proliferation as measured by Ki67 evaluation. Patients were followed for 2 years. Of the 23 patients were enrolled, 3 were excluded. At the end of the 3 treatment cycles, the patients presented clinical improvement in the mean number of hairs, with a mean increase of 33.6 hairs in the target area and a mean increase in total hair density of 45.9 hairs per cm2 compared with baseline values. No side effects were noted during treatment. Microscopic evaluation showed the increase of epidermis thickness and of the number of hair follicles 2 weeks after the last PRP treatment compared with baseline value (p<0.05). We also observed an increase of Ki67+ keratinocytes in the epidermis and of hair follicular bulge cells and a slight increase of small blood vessels around hair follicles in the treated skin compared with baseline (p<0.05). Relapse of androgenic alopecia was not evaluated in all patients until 12 months after the last treatment. After 12 months, 4 patients reported progressive hair loss; this was more evident 16 months after the last treatment. Those four patients were re-treated. Our data clearly highlight the positive effects of PRP injections on male pattern hair loss and absence of major side effects. PRP may serve as a safe and effective treatment option against hair loss; more extensive controlled studies are needed.
Biography

Pietro Gentile is a Chief of Teaching of Plastic and Reconstructive Surgery at the Catholic University “Our Lady of Good Counsel” in Tirana, Albania. He received the Enabling Associate Professor in Plastic and Reconstructive Surgery in February 2014. He is currently Research Fellow at the University of Rome “Tor Vergata”. He received the PhD in Regenerative Surgery at the University of Rome “Tor Vergata”. He is Author of the book “THE ADIPOSE TISSUE” published by Monduzzi, ISBN 978-88-6521- 075-8. He is Author of the book “Regenerative Plastic Surgery” published by SEU, ISBN 978-88-6515-112-9. He is author, co-author of No. 79 publications.

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords