alexa The Effect Of Stomach PH On The Bioavailability Of Weakly Basic Oncology Drugs And Formulations Options To Reduce Exposure Variability
ISSN: 0975-0851

Journal of Bioequivalence & Bioavailability
Open Access

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5th World Congress on Bioavailability and Bioequivalence Pharmaceutical R&D Summit
September 29-October 01, 2014 DoubleTree by Hilton Baltimore-BWI Airport, USA

Faraj Atassi
Accepted Abstracts: J Bioequiv Availab
DOI: 10.4172/0975-0851.S1.019
Abstract
T he development of Pharmaceutical formulations shifted from traditional formulations towards ?Novel Drug Delivery System?. At the same time new drug molecules having better therapeutic response are also being introduced. Besides this, there are several new polymers introduced by ?Polymer Scientist? useful in development of ?Novel Drug Delivery System? of new molecule for better and desired therapeutic action in patients. Evaluation of formulation is being done after its development. Dissolution study is one of them, for doing in vitro study of formulation for knowing its release from the used polymer of developed formulation at desired rate. But for knowing its availability in biological system the in vivo study is being conducted known as ?Bioavailability study?. Further since several scientists are developing formulations of similar molecules at different places, hence the Bioequivalence study is become a necessity of those formulations. In view of above for providing better therapeutic response in patients with minimum & modified dose, the ?Bioavailability and Bioequivalence study? is the need of hour for patient safety.
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