alexa The Heart Is A Target Organ In Offspring Rats Due To Maternal Hereditary Hypertension Or Nitric Oxide Synthesis Inhibition
ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

4th International Conference on Clinical & Experimental Cardiology
April 14-16, 2014 Hilton San Antonio Airport, TX, USA

Sonia Regina Jurado
Posters: J Clin Exp Cardiolog
DOI: 10.4172/2155-9880.S1.020
Abstract
The aim of this study was to analyze the effect of hereditary hypertension or induced by chronic nitric oxide inhibition during pregnancy on the structural changes in rats fetal and neonate coronary microvessels, aorta and myocardial collagen content. Total nine sub-groups allocated from three main groups of fetuses (20 th d) and newborns (2 nd and 15 th d) offspring?s from normotensive mothers (C), SHR and L-NAME were studied. Heart and aorta sections were stained by hematoxylin and eosin, Mallory?s thichrome, Picrosirius red and periodic acid-schiff reagent. Pro-Plus image analysis system was used to assess the thickness of aorta and myocardial vessels. The tunica media inner and outer border was traced in each micro vessel (external diameter < 50 um) image at x100 and, in aorta at x 400 magnification, and areas encircled by tracings were calculated. The significant difference (*) was considered if P<0.05. Aorta wall area and wall-to-lumen ratio increased in hypertensive animals in all ages. The number of elastic lamellae was reduced in hypertension (L-NAME: 7.00?0.16* and SHR: 7.30?0.19) at 15 th d compared to C (7.60?0.17). The Microvessels wall area was greater in hypertensive offspring at 15 th d. Lumen area and external perimeter decreased in both hypertension models at 15 th d. Wall-to-lumen ratio increased in hypertensive at 2 nd and 15 th d. Collagen content (%) was higher in SHR at 2 nd d (0.74?0.02*) and 15 th d (2.53?0.04*) and in L-NAME at 15 th (2.25?0.04*) versus C (0.61?0.02 at 2 nd d and 2.12?0.05 at 15 th d). Maternal hypertension burdens cardiovascular consequences as described for adult animal?s hypertension
Biography
Sonia Regina Jurado is graduated in Biological Sciences from the State University of Rio de Janeiro (1995), master in Morphology from the State University of Rio de Janeiro (1998) and Ph.D. in Pathophysiology in Clinical Medicine from the Universidade Estadual Paulista J?lio de Mesquita Filho (2005), Brazil. She is an Associate Professor in the Nursing Course at the Federal University of Mato Grosso do Sul (UFMS) and tutor group Tutorial Education in Nursing/UFMS. Professor Jurado has experience in the area of Medicine, Nursing and Biology . She has among papers in scientific journals and conference proceedings
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immun[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords