alexa The Observation Of The Immunization Effect Of Hepatitis B Vaccine To The Newborn With HBeAg Positive
ISSN: 2157-7560

Journal of Vaccines & Vaccination
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

3rd International Conference on Vaccines & Vaccination
July 29-31, 2013 Embassy Suites Las Vegas, NV, USA

Zhang Ping, Lu Wei and You Wei
ScientificTracks Abstracts: J Vaccines Vaccin
DOI: 10.4172/2157-7560.S1.016
Abstract
U sing the same dose of hepatitis B vaccine, HBsAg negative and HBeAg-positive newborns can produce higher and more sustained amount of anti-HBs than HBeAg-negative newborns birthed by HBV infected mothers, suggesting the effect of the presence of HBeAg and hepatitis B vaccine simultaneously on the anti-HBs is worth to discuss. With the approval of the ethical argument, we observed 460 cases of hepatitis B virus carriers (HBVDNA≥106), the venous blood detection of HBsAg of all the newborns were negative within 2 hours of birth, 234 HBeAg negative cases of experimental group at birth quantitative M (P25, P75) was 48000 (23.875, 86.050), 226 cases of control group was HBeAg-negative. Both groups were injected with hepatitis B immune globulin 200 IU within 6 hours after birth , and 10μg hepatitis B vaccine immunization at 0, 1, 6 months. When they are 2 years old, the anti-HBs detection M (P25, P75) of study group was 456.850 (312.900, 652.325), the control group M (P25, P75) was 149.800 (65.300, 343.400). Statistically, Z=-9.963, p<0.01. When they are 5 years old, detection of anti-HBs group M (P25, P75) was 612.600 (366.025, 982.550) and control group M (P25, P75) was 215.00 (51.05, 478.15). Statistically, Z=-8.260, P<0.01. Both groups were HBsAg negative. Concluded that the presence of serum HBeAg in newborns may be more sensitive to immune response of hepatitis B vaccination, resulting in higher and more long-lasting anti-HBs we point out that combination use of HBeAg and hepatitis B vaccine may increase the immunogenicity of hepatitis B vaccine. Keywords: HBeAg-positive, newborns, immune effect.
image PDF   |   image HTML
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords