This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
The pulmonary vein isolation remains the major target of atrial fibrillation ablation. The cryoablation lesions in the left atrium
are supposed to disconnect the pulmonary vein from the atrium on the atrial side of the orifices. We hypothesized that the
cryoballoon pulmonary vein isolation could result in the prolongation of the P wave duration.
The aim of the study was to assess the duration of the P wave in 12-lead electrocardiogram and the influence of pulmonary
vein isolation on this parameter.
The study group included 29 patients (14 women and 15 men) 69.1+/-7.1 years of age undergoing cryoballoon ablation. In
order to measure the P wave duration, we used the constant acquisition of electrogram and the electrocardiographic channels
provided by LABSYSTEM??? Pro EP Recording System (Boston Scientific), magnifying the leads 64x. We calculated the duration
in the simultaneously recorded 12-lead ECG, from the beginning of the earliest recorded P wave deflection, until the end of
the latest P-wave deflection recorded in any lead. The P wave duration in the entire study group was 144.8+/- 13.6 ms before
the ablation and increased significantly to 158.3+/-14.5 ms (p<0.05) after the procedure. The mean standard deviation of every
single measurement considered separately was 4.6+/- 2.5 ms before the cryoablation and 4.7+/-1.9 ms after the procedure (p=
n.s.), indicating very good reproducibility of the measurements.
The cryoballoon pulmonary vein isolation leads to the prolongation of the measured P wave duration. It seemed to result from
conduction disturbances created by cryoablation. The clinical significance of the observed changes remains unknown.
Jacek Gajek has completed his MD at the age of 25 years from Wroclaw Medical University and postdoctoral studies from Wroclaw Medical University achieving PhD. He is the head of the Department of Internal Nursing in Deparment of Clinical Nursing at Wroclaw Medical University and a sucessful cardiologist and electrophysiologist. He has published more than 60 papers in cardiology journals and has been serving as an editorial board member of Advances in Clinical and Experimental Medicine.