alexa The Prognostic Utility Of Pre-treatment 18F-FDG-PET For Salvage Re-irradiation In Head And Neck Cancer Patients
ISSN: 1948-5956

Journal of Cancer Science & Therapy
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

14th World Cancer & Anti-Cancer Therapy Convention
November 21-23, 2016 Dubai, UAE

Kateryna Musaiev
Clinical Hospital Feofaniya, Ukraine
Posters & Accepted Abstracts: J Cancer Sci Ther
DOI: 10.4172/1948-5956.C1.094
Abstract
Background: Statistical image features of tumor metabolism from pretreatment 18F-FDG-PET/CT scans were studied for their potential to predict clinical outcome of salvage re-irradiation with intensity modulated radiotherapy (IMRT) for recurrent squamous cell carcinoma of head and neck (HNSCC). Materials & Methods: Pretreatment PET/CT scans and after treatment PET/CT scans of patients who underwent IMRT re-irradiation for recurrent HNSCC, were retrospectively evaluated. Metabolic response was assessed using PET response criteria for solid tumors (PERCIST). Multiple statistical image features related to the standard uptake value (SUV) were computed: Metabolic tumor volume, maximum SUV, mean SUV and total lesion glycolysis (TLG). The correlation between the image features and local control and overall survival was calculated. Results: Complete tumor metabolic response (CMR) was achieved in 5 patients (45.5%). Six (6) patients failed to achieve CMR: Progressive metabolic disease was in 4 patients (36.4%); stable metabolic disease in 1 patient (9.1%); and 1 patient had partial metabolic response (9.1%). The median follow-up time was 18.2 months. Out of the calculated image features, only pre-treatment tumor TLG (individual tumor volume multiplied by its mean SUV) correlated with tumor metabolic response in the early PET/CT follow-up. Also dividing the patient population based on the median tumor TLG showed a split of the Kaplan-Meier survival curves. Conclusions: The tumor TLG of pre-treatment PET/CT scans has important information on the failure risk to achieve CMR in recurrent HNSCC patients. It is necessary to obtain additional patients data to validate these results.
Biography

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords