alexa Thrombosis In A Patient With Thrombocytopenia
ISSN: 2165-7920

Journal of Clinical Case Reports
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

5th European Conference on Clinical and Medical Case Reports
September 07-08, 2017 Paris, France

Ebtisam Alhuwaidi
Geriatric Health Services Administration, UAE
Posters & Accepted Abstracts: J Clin Case Rep
DOI: 10.4172/2165-7920-C1-012
Abstract
Cerebral venous thrombosis (CVT) is an acute life-threatening condition that usually occurs due to an underlying hypercoagulable state. The infrequency with which it presents insidiously and with underlying thrombocytopenia makes it a formidable diagnostic challenge. A 43-year-old woman presented with 1-month history of intermittent throbbing bi-temporal headache mild to moderate in severity, associated with nausea, vomiting, and blurring of vision not responding to analgesics. Her past medical history includes diabetes, hypertension, dyslipidemia, obesity and a 3-year history of menorrhagia. Neurological examination revealed bilateral papilledema. No evidence of meningism or focal neurological deficit. General examination and that of other systems was normal. Investigations showed microcytic hypochromic anemia (Hb: 7.5 g/dl), low platelet count (63,000), normal coagulation profile. Screening for vasculitis came back normal. No source of active bleeding or any malignant disease was found on upper/lower GI endoscopies. MRI brain and MR venography revealed right transverse, sigmoid sinus and right internal jugular vein thrombosis. Lumbar puncture showed high opening pressure, with no cells, normal glucose and protein. The patient was treated with low molecular weight heparin, later switched to warfarin tablets. Iron tablets were also started to correct the anemia. Daily hemogram showed rapid platelet correction within a week (200,000). The patient's symptoms improved gradually. Upon discharge, the patients Hb improved slightly *8.2 g/dl) and the platelet count came up to 336,000. The cause of anemia was presumed to be due to the longstanding menorrhagia, after ruling out all other possible causes. One theory to explain the link between IDA and thrombosis is that the increased viscosity, oxidative stress and cell deformability found in IDA, may contribute directly to a hypercoagulable state within the vessels. This case illustrates the potential for CVT to occur simultaneously with thrombocytopenia and anemia. The correction of iron deficiency rapidly restores the platelet count as well, which may contribute to the reversal of symptoms, in the presence of adequate anticoagulation. Whether the menorrhagia is an independent risk factor for a hypercoagulable state has yet to be studied. Recognition of this rare but possible scenario is critical to the timely initiation of appropriate therapy.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]sonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords