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Breast cancer (BC) is the most common cause of cancer ? related mortality in women. Th
e main cause of mortality in this
group is generalization of BC with development of polyorganic insuffi
ciency in the background of chronic pain syndrome.
In this connection the choice of rational methods of palliative therapy remains actual, especially in cases with multiple aff
Objective of the study was to evaluate the volume of palliative chemoradiation therapy implamantation to increase the survival
rate of patients.
To research were included 23 women with disseminated breast cancer (DBC) at the age of 34-60 years and they were divided
into 2 groups: Th
group consisted of 13 women with distant metastases in liver, bones of skeleton and skin. Th
consisted of 10 women with metastases in supraclavicular lymph nodes of aff
ected site, in liver and bones of skeleton. Patients
rst group in the background of palliative polychemotherapy (PPCT) (4-6 cycles) ? taxanes with anthracyclines, received
shortfocal therapy in the region of intradermal metastases. Patients of second group received similar PPCT with palliative
radiation therapy in supraclavicular region ? 40-44 Gy. Patients of both group under control of blood Calcium levels received
In patients with DBC in both of group average time for disease progression as development of polyorganic insuffi
sharp limitation of specialized therapy arsenal was 8.7 months. In addition to that local disease control ? without signs of
lymphostasis and limitations in volume of movement in upper extremity of aff
ected site without impairment of patient?s life
quality was marked.
Implementation of palliative chemoradiation and X-ray therapy in patients with DBC allows to increase average time of disease
progression and life quality of fatally diseased patients with DBC.
Khakimov Golib Abdullayevich: MD, Professor. Head of Department of Oncology in Tashkent Pediatric Medical Institute. Has publis
hed more than
100 papers in reputed journals.
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