Natural Products Chemistry & Research

ISSN - 2329-6836

Two new polychiral pyrones from Orthosiphon diffusus

3rd International Conference and Exhibition on Pharmacognosy, Phytochemistry & Natural Products

October 26-28, 2015 Hyderabad, India

Akanksha Sharma1, Harish Holla1 and Biswanath Das2

1Central University of Karnataka, India 2Indian Institute of Chemical Technology, India

Posters-Accepted Abstracts: Nat Prod Chem Res

Abstract :

Chemical investigation on Orthosiphon diffusus resulted in the isolation of two new polychiral furanopyrans, orthodiffenes E-F (5- 6) along with earlier reported polychiral furanopyrans, orthodiffenes A-D (1-4). The new molecules were characterized from the detailed studies of their 1D, 2D NMR spectra and mass spectra. Orthodiffenes A-D (1-4) has been reported earlier to be significantly cytotoxic against cancer cell lines. The new molecules orthodiffenes E-F (5-6) are expected to be cytotoxic against cancer cell lines due to structural similarity to orthodiffenes A-D (1-4).

Biography :

Akanksha Sharma is a Research Scholar pursuing her PhD from Central University of Karnataka. She has completed her MPharm from Central University of Punjab.

Email: akanksha.rph@gmail.com

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