alexa Use Of Induction Chemotherapy For Advanced Stage Oral Cavity Squamous Cell Carcinoma | 72689
ISSN: 2161-1122

Dentistry
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

24th World Congress on Dentistry and Oral Health

Saurin R. Popat
University of Buffalo School of Medicine & Dentistry, USA
ScientificTracks Abstracts: Dentistry
DOI: 10.4172/2161-1122-C1-017
Abstract
Oral cavity squamous cell carcinoma (OC-SCCa) accounts for nearly 1/3 of all head and neck squamous cell cancers in the US however with significant international geographic variation due to carcinogen exposure and availability. The mainstay of treatment for resectable disease had been surgery with postoperative radiation based on specific clinical and pathologic features. Survival rates have little improved prior to the use of concurrent postoperative chemoradition. Since 2009, we have employed induction chemotherapy (ICT) as an option to be added to the comprehensive treatment of OC-SCCa. A review of our outcomes was conducted. Patients/Methods: Retrospective review from 2010 -2015 of patients with stage IV OC-SCCa with minimal 24 month follow-up who received ICT and with no previous history of treated head & neck SCCa. 59 patients were identified however 6 met inclusion criteria. All received 2 to 3 cycles of ICT consisting of cisplatin and either fluorouracil and/or a taxane. Following IHC, all underwent surgical resection. Results: Survival from OC-SCCa was 100% with 4 patients NED and 2 patients DOC/NED. Median survival was 54.3 months. Three patients had ICT complications but recovered and proceeded to surgery. There were 3 surgical complications in 2 patients. Historic literature based on AJCC data has survial at 4.5 years to be approximately 29%. Conclusions: Though the study size is small, ICT demonstrated excellent tumor response in our patient population with enduring and superior disease free survival. A larger multicenter trial would be required to confirm these results and outline chemotherapy drug selection.
Biography

Saurin R. Popat has completed Doctorate of Medicne from the University of Western Ontario, London, Canada in 1992, followed by an Otolaryngology – Head & Neck Surgery Residency at the University of Toronto in 1997 and two Fellowships in Head & Neck Surgical Oncology/Microvascular Reconstruction at the University of Toronto (1999) and Skull Base Surgery in Switzerland (2000). He completed an MBA from Cornell University (2010) and serves as Director of Head & Neck Surgery at the Comprehensive Head & Neck Center (CHANCe) in Buffalo, NY with more than 30 publications and book chapters.

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7