Reach Us +441414719275
Wound Healing Activity Study Of Commiphora Myrrha Engl. (Burceraceae); Using In Vivo And In Vitro Experiments | 9646
ISSN: 2157-7552

Journal of Tissue Science & Engineering
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

2nd International Conference on Tissue Science & Regenerative Medicine

Michael Gebrehiwot
Accepted Abstracts: J Tissue Sci Eng
DOI: 10.4172/2157-7552.S1.012
B ased on ethnobotanical claims, the oleo-gum-resin of Commiphora myrrha was investigated for its potential wound healing activity using in vivo and in vitro models. Wound healing activity was studied by topical application of an ointment of the essential oil 4% (v/w) and the resin 5% (w/w).Toxicity of the formulated ointment upon topical application was studied according to Draize skin irritation test. For anti inflammatory study, carrageen an induced hind paw oedema model was used. The free radical scavenging activity was studied using DPPH assay. The antimicrobial activity of the extracts was examined using disk diffusion and broth dilution technique against several pathogenic bacterial and fungal strains. The ointment formulations of the extracts were found to be non-irritant at the concentrations used .Treatment of wound with the ointments prepared from the essential oil and resin of C. myrrha exhibited significant (p<0.05-0.001) increase in wound contraction rate, shorter epithelization time and higher skin breaking strength as compared to the control. A significant (p<0.05) reduction of inflammation was also observed, as compared to the control. The antibacterial and antifungal activity of the oil and the resin was comparable with the standard antibiotics ciprofloxacin and griseofulvin, respectively. From the results obtained in the present study, the essential oil and resin of C. myrrha enhance wound healing activity most likely via anti inflammatory, antimicrobial and free radical scavenging effects, supporting the traditional use of this plant as wound healing agent.
Michael Gebrehiwot has completed his B.Pharm at the age of 22 from Mekelle University in 2008 and B.Sc.. studies from Addis Ababa University, School of Pharmacy on October 2012. He is now an academic staff in Mekelle University; he gives lecture, advice undergraduate students and conduct research. His paper is accepted by Phytopharmacology journal and he also submitted another paper to Journal of Ethnopharmacology
image PDF   |   image HTML

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7