alexa 5-Aza-CdR delivers a gene body blow.
Pharmaceutical Sciences

Pharmaceutical Sciences

Journal of Molecular Pharmaceutics & Organic Process Research

Author(s): Kasinathan S, Henikoff S

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Abstract In this issue of Cancer Cell, Yang et al. describe a causal relationship between gene body methylation and gene expression and a role for genic methylation in response to clinical DNA methylation inhibitors, which suggests that the mechanism of action of these inhibitors includes gene body hypomethylation-induced downregulation of cancer-associated genes. Copyright © 2014 Elsevier Inc. All rights reserved.
This article was published in Cancer Cell and referenced in Journal of Molecular Pharmaceutics & Organic Process Research

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