alexa A 3D paired microelectrode array for accumulation and separation of microparticles
Biomedical Sciences

Biomedical Sciences

Journal of Bioengineering & Biomedical Science

Author(s): D F Chen, H Du, W H Li

Abstract Share this page

This paper presents a microfluidic system comprising a three-dimensional microelectrode structure for accumulation and separation of micro-sized particles based on the combination of negative dielectrophoresis (DEP) and hydrodynamic force. The paired electrode array is constructed by aligning two layers of microelectrode structure face to face on the top and bottom sides of the microchannel. Dielectrophoretic gates are generated between the top and bottom electrodes with high-frequency ac voltage. These gates are designed to study the behavior of microparticles such as polystyrene beads or cells carried by a laminar flow past the electrodes. Depending on the relative strength of the DEP force and hydrodynamic force acting on the particles, the particles can either penetrate the gates or settle by the gates. The threshold velocity at which the particles begin to penetrate the gates depends on a number of parameters such as channel height, particle size, dielectric properties, electrode width and local heating, etc. A wide range of these parameters give rise to approaches of accumulating and separating microparticles. For this purpose, a microfluidic device with the paired microelectrode array sitting on the channel has been designed and fabricated using microfabrication techniques. Polystyrene beads were used to study the performance of the device and particle behavior. Using a proper range of flow rates, particle accumulation and separation are successfully achieved with the microsystem.

  • To read the full article Visit
  • Open Access
This article was published in Journal of Micromechanics and Microengineering and referenced in Journal of Bioengineering & Biomedical Science

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords