alexa [A cardiac lesion secondary to paraquat].


Journal of Clinical Toxicology

Author(s): Pvoa R, Maciel FM, Orlando JM, Pvoa EF, Honsi E,

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Abstract PURPOSE: To evaluate cardiac alterations secondary to exogenous intoxication by paraquat. METHODS: We performed analysis of clinical and laboratory data of 25 patients with acute paraquat poisoning admitted in our ICU from November 1983 to January 1991. RESULTS: There were purposeful overdoses in 24 cases (96\%). The mortality rate was 56\%. The lung involvement was 96\%, renal was 92\%, gastrointestinal tract was 72\%, hepatic was 56\%, and cardiac involvement was 40\%. CONCLUSION: Cardiac involvement due to paraquat is frequent (40\%). The clinical picture of this involvement has a wide spectrum, ranging from minimal changes in the ECG to acute and extensive myocardial necrosis.
This article was published in Arq Bras Cardiol and referenced in Journal of Clinical Toxicology

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