alexa A neuron-based time-optimal controller of horizontal saccadic eye movements.
Biomedical Sciences

Biomedical Sciences

Journal of Biomedical Engineering and Medical Devices

Author(s): Ghahari A, Enderle JD

Abstract Share this page

Abstract A neural network model of biophysical neurons in the midbrain for controlling oculomotor muscles during horizontal human saccades is presented. Neural circuitry that includes omnipause neuron, premotor excitatory and inhibitory burst neurons, long lead burst neuron, tonic neuron, interneuron, abducens nucleus and oculomotor nucleus is developed to investigate saccade dynamics. The final motoneuronal signals drive a time-optimal controller that stimulates a linear homeomorphic model of the oculomotor plant. To our knowledge, this is the first report on modeling the neural circuits at both premotor and motor stages of neural activity in saccadic systems. This article was published in Int J Neural Syst and referenced in Journal of Biomedical Engineering and Medical Devices

Relevant Expert PPTs

Relevant Speaker PPTs

  • Francesco Fontana
    Wearable artificial kidney - back to the future: A review
    PPT Version | PDF Version
  • Mario Marques da Silva
    MIMO Systems and Applications
    PPT Version | PDF Version
  • Mehdi Shadaram
    Photonic Generation of Millimeter Wave Signals for Wireless Applications
    PPT Version | PDF Version
  • Trung-Dinh Han
    Device-To-Device (D2D) Communication in 5G Cellular Networks
    PPT Version | PDF Version
  • Zaid A Shafeeq
    A Wireless Cognitive Radio Network with a Synchronized Cooperative Relaying
    PPT Version | PDF Version
  • Elizabeth Chang
    Advances in Internet of Things and Cyber Physical Systems and its Adoption to Smart Ship
    PPT Version | PDF Version
  • Qilian Xie
    Accompanying mild hypothermia significantly improved the prognosis of septic mice than artificial mild hypothermia
    PPT Version | PDF Version
  • Albert Owusu
    Albert-Owusu-Bana-Consulting-Engineers-Australia-Rethinking-the-Application-of-Engineering-Structural-Analysis-of-Economic-Impact-Risk-Propagation-in-Infra-structures
    PPT Version | PDF Version
  • Antoine N. Gergess
    Antoine N. Gergess-University-of-Balamand-Lebanon-Cold-Bending-Steel-Beams-a-State-of-The-Art-Engineering-Solution-that-Meets-Industry-Challenges
    PPT Version | PDF Version
  • AbdulQader S. Al-Najmi
    Abdul-Qader-S-Al-Najmi-Jordan-University-School-of-Engineering-Jordan-Towards-the-Design-of-Super-Columns
    PPT Version | PDF Version
  • Shree Kumar Apte
    Genetic engineering of Deinococcus radiodurans for uranium bioremediation from high radiation environment
    PPT Version | PDF Version
  • Tamar Ben-Bassat
    Tamar-Ben-Bassat-Sami-Shamoon-College-of-Engineering-Israel-Israeli-and-American-traffic-signs-–-similarities-differences-and-compliance-with-ergonomic-principles-of-signs-desi
    PPT Version | PDF Version
  • Yosef Yarden
    Classically, the 3’untranslated region (3’UTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3’UTR alone, without all other elements in mRNA such as 5’UTR and coding region. The importance of independent 3’UTR RNA (referred as I3’UTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3’UTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3’UTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3’UTR were important for its tumor suppression activity. Then, the C/EBP 3’UTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3’UTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3’UTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990’s to 2000’s, world scientists found several 3’UTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3’UTR regions, although the existence of their transcribed products as independent 3’UTR RNAs is still to be confirmed. Our studies indicate that the independent 3’UTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole.
    PPT Version | PDF Version
  • Veronica La Regina
    Veronica-La-Regina-Italian-Space-Agency-(ASI)-Italy-Systems-engineering-approach-and-space-technology-transfer-The-role-of-international-relations-and-public-policy
    PPT Version | PDF Version
  • S M Pérez-Moreno
    Potential valorizations of artificial gypsum generated in the manufacture of titanium dioxide pigments
    PPT Version | PDF Version
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsonline.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsonline.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsonline.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsonline.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsonline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsonline.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsonline.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsonline.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version