alexa A new anti-oestrogenic agent in late breast cancer. An early clinical appraisal of ICI46474.
Genetics & Molecular Biology

Genetics & Molecular Biology

Journal of Genetic Syndromes & Gene Therapy

Author(s): Cole MP, Jones CT, Todd ID

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Abstract An introductory clinical trial of the anti-oestrogenic agent IC146474 in late or recurrent carcinoma of the breast is described.Forty-six patients have been treated, of whom 10 have shown a good response. This is of the same order as that seen with oestrogens and androgens.The particular advantage of this drug is the low incidence of troublesome side effects.
This article was published in Br J Cancer and referenced in Journal of Genetic Syndromes & Gene Therapy

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