alexa A novel therapeutic option in Cogan diseases? TNF-alpha blockers.
Clinical Research

Clinical Research

Journal of Clinical Case Reports

Author(s): Fricker M, Baumann A, Wermelinger F, Villiger PM, Helbling A

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Abstract Cogan's syndrome is characterized by noninfectious, interstitial keratitis combined with a vestibulo-auditory deficit. Despite therapy with corticosteroids in combination with immunosuppressive agents, relapses occurred in two subjects and the clinical course suggested a progression of the disease. Treatment with anti-TNF-alpha was started leading to a rapid and sustained clinical remission for over 2 respectively 3 years. This article was published in Rheumatol Int and referenced in Journal of Clinical Case Reports

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