alexa A piperidine amide extracted from Piper longum L. fruit shows activity against Aedes aegypti mosquito larvae.
Agri and Aquaculture

Agri and Aquaculture

Journal of Fertilizers & Pesticides

Author(s): Yang YC, Lee SG, Lee HK, Kim MK, Lee SH,

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Abstract Mosquito larvicidal activity of Piper longum fruit-derived materials against the fourth-instar larvae of Aedes aegypti was examined. A crude methanol extract of P. longum fruits was found to be active against the larvae, and the hexane fraction of the methanol extract showed a strong larvicidal activity of 100\% mortality. The biologically active component of P. longum fruits was characterized as pipernonaline by spectroscopic analyses. The LC(50) value of pipernonaline was 0.25 mg/L. The toxicity of pipernonaline is comparable to that of pirimiphos-methyl as a mosquito larvicide. In tests with available components derived from P. longum, no activity was observed with piperettine, piperine, or piperlongumine.
This article was published in J Agric Food Chem and referenced in Journal of Fertilizers & Pesticides

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