Author(s): Szkudliski MW
Abstract Share this page
Abstract The exact mechanism of anticancer activity of indomethacin still remains unclear. In view of the gathered observations and ideas, I hypothesize that the effect of indomethacin may be related--at least in certain cases--to its antagonism to gastrin/cholecystokinin family of peptides and/or to its agonistic activity to thromboxane A2 and melatonin. Future experiments in this direction are required.
This article was published in Med Hypotheses
and referenced in Journal of Nanomedicine & Nanotechnology