alexa A prospective, randomized, double-blind comparison of articaine and lidocaine for maxillary infiltrations.


Emergency Medicine: Open Access

Author(s): Evans G, Nusstein J, Drum M, Reader A, Beck M

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Abstract The purpose of this prospective, randomized, double-blind crossover study was to evaluate the anesthetic efficacy of 4\% articaine with 1:100,000 epinephrine and 2\% lidocaine with 1:100,000 epinephrine in maxillary lateral incisors and first molars. Eighty subjects randomly received, in a double-blind manner, maxillary lateral incisor and first molar infiltrations of one cartridge of 4\% articaine with 1:100,000 epinephrine or 2\% lidocaine with 1:100,000 epinephrine at two separate appointments spaced at least 1 week apart. In maxillary lateral incisors, articaine exhibited a significantly higher anesthetic success rate of 88\% when compared with a 62\% success rate with lidocaine. In maxillary first molars, articaine had a similar success rate to lidocaine (78\% vs 73\%), and there was no significant difference between the two solutions. In conclusion, a maxillary infiltration of 4\% articaine with 1:100,000 epinephrine statistically improved anesthetic success when compared with 2\% lidocaine with 1:100,000 epinephrine in the lateral incisor but not in the first molar. This article was published in J Endod and referenced in Emergency Medicine: Open Access

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