Author(s): Prajna NV, John RK, Nirmalan PK, Lalitha P, Srinivasan M
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Abstract AIM: To compare 2\% econazole and 5\% natamycin in the management of fungal keratitis. METHODS: A randomised clinical trial was performed using 2\% econazole or 5\% natamycin as the two treatment arms on patients presenting with culture positive fungal keratitis to the cornea service at Aravind Eye Care System, Madurai, India. RESULTS: 116 patients were recruited, and 112 continued in the study. There were no significant differences between the two arms at baseline or for success (defined as a healed or healing ulcer) at final visit (p = 0.79). CONCLUSIONS: 2\% Econazole appears to be as effective as 5\% natamycin for the management of fungal keratitis.
This article was published in Br J Ophthalmol
and referenced in Fungal Genomics & Biology