alexa A review of toxicity from topical salicylic acid preparations.
Chemistry

Chemistry

Natural Products Chemistry & Research

Author(s): Madan RK, Levitt J

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Abstract Topical salicylic acid is often used in dermatologic conditions because of its keratolytic, bacteriostatic, fungicidal, and photoprotective properties. The bioavailability of salicylic acid differs depending on the vehicle used and pH of transcellular fluids. Although rare, salicylic acid toxicity (salicylism) can occur from topical application. Physicians should be mindful of the potential for salicylism or even death from topically applied salicylic acid. Copyright © 2013 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved. This article was published in J Am Acad Dermatol and referenced in Natural Products Chemistry & Research

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