Author(s): Wennekamp S, Mesecke S, Ndlec F, Hiiragi T
Abstract Share this page
Abstract The mechanisms underlying the appearance of asymmetry between cells in the early embryo and consequently the specification of distinct cell lineages during mammalian development remain elusive. Recent experimental advances have revealed unexpected dynamics of and new complexity in this process. These findings can be integrated in a new unified framework that regards the early mammalian embryo as a self-organizing system.
This article was published in Nat Rev Mol Cell Biol
and referenced in Current Synthetic and Systems Biology