alexa A systematic review of severe morbidity in infants born late preterm.
Pediatrics

Pediatrics

Journal of Neonatal Biology

Author(s): Teune MJ, Bakhuizen S, Gyamfi Bannerman C, Opmeer BC, van Kaam AH,

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Abstract OBJECTIVE: Late-preterm infants (34 weeks 0/7 days-36 weeks 6/7 days' gestation) represent the largest proportion of singleton preterm births. A systematic review was performed to access the short- and/or long-term morbidity of late-preterm infants. STUDY DESIGN: An electronic search was conducted for cohort studies published from January 2000 through July 2010. RESULTS: We identified 22 studies studying 29,375,675 infants. Compared with infants born at term, infants born late preterm were more likely to suffer poorer short-term outcomes such as respiratory distress syndrome (relative risk [RR], 17.3), intraventricular hemorrhage (RR, 4.9), and death <28 days (RR, 5.9). Beyond the neonatal period, late-preterm infants were more likely to die in the first year (RR, 3.7) and to suffer from cerebral palsy (RR, 3.1). CONCLUSION: Although the absolute incidence of neonatal mortality and morbidity in infants born late preterm is low, its incidence is significantly increased as compared with infants born at term. Copyright © 2011 Mosby, Inc. All rights reserved. This article was published in Am J Obstet Gynecol and referenced in Journal of Neonatal Biology

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