alexa A TeNaCious foundation for the metastatic niche.


Journal of Carcinogenesis & Mutagenesis

Author(s): Matei I, Ghajar CM, Lyden D

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Abstract In the July issue of Nature Medicine, Massagué and colleagues define a biphasic role for the extracellular matrix protein tenascin C as a metastatic niche component in lung colonization by breast cancer cells. These results provide a rationale for designing therapies targeting metastatic progression by disrupting its very foundations. Copyright © 2011 Elsevier Inc. All rights reserved. This article was published in Cancer Cell and referenced in Journal of Carcinogenesis & Mutagenesis

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