Author(s): Blatnik J, Jin J, Rosen M
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Abstract BACKGROUND: The ability of biologic mesh to remodel into native fascia and prevent hernia recurrence in complicated repairs is appealing. However, few long-term data exist evaluating these products in the setting of bridging fascial defects. These collagen-based mesh products are costly, and long-term evaluation of hernia recurrence rates are necessary to justify their expense. METHODS: This was a retrospective review of patients undergoing repair of complex abdominal defects with acellular dermal matrix (ADM) at our institution was performed. RESULTS: Between January 2004 and December 2005, 11 patients underwent complex ventral hernia repairs with bridging ADM. Indications for repair included resection of enterocutaneous fistula, infected mesh, and/or ventral hernia repair. A mean of 175 cm(2) (range 8 to 456) of ADM were used. Mean follow-up was 24 months (range 18 to 37). One patient died on postoperative day 20. Eight of the 10 (80\%) remaining patients had recurrences, and 7 underwent further surgery for repair. One patient reported laxity but refused repair. The total cost of ADM alone for these 11 patients was $61,926; the cost for the 8 patients having recurrences was $40,776; and the total mean cost was $5,100/patient. CONCLUSIONS: Although bridging fascial defects with ADM can be an appealing substitute in extremely complicated cases, our data demonstrate exceedingly high recurrence rates. The long-term outcome of bridging fascial defects with biologic prosthesis does not justify the expense of the product.
This article was published in Am J Surg
and referenced in Journal of Agricultural Science and Food Research