alexa Ability to smell androstenone is genetically determined.
Pharmaceutical Sciences

Pharmaceutical Sciences

Journal of Pharmacogenomics & Pharmacoproteomics

Author(s): Wysocki CJ, Beauchamp GK

Abstract Share this page

Abstract Some adult humans cannot detect the odor of androstenone (5 alpha-androst-16-en-3-one), a volatile steroid. To test for the presence of genetic variance associated with this trait, adult twins were tested for their ability to smell androstenone and another odorant, pyridine, that is readily perceived by most adults. Ascending concentration, two-sample (odor versus blank) forced choice tests were used to assess sensitivity to these odorants. Intraclass correlations for identical and fraternal twin detection thresholds to pyridine were small and not significantly different. However, intraclass correlations for thresholds to androstenone were significantly different, with the correlation for identical twins being greater than that for the fraternal twins. These data indicate a genetic component of variation in sensitivity to this odor. Investigations that use genetic variation could offer a new tool for studies of olfactory transduction mechanisms.
This article was published in Proc Natl Acad Sci U S A and referenced in Journal of Pharmacogenomics & Pharmacoproteomics

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords