alexa Abnormal biochemical and haematological indices in trypanosomiasis as a threat to herd production.
Pharmaceutical Sciences

Pharmaceutical Sciences

Journal of Clinical & Experimental Pharmacology

Author(s): Ohaeri CC, Eluwa MC

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Abstract Blood samples were collected from 46 domestic ruminants comprising of 23 trypanosomiasis infected and 23 uninfected control groups to study some biochemical and haematological effects of trypanosomiasis under natural condition. The effect of trypanosome infection in ruminant animals showed that infected animals had significantly lower (P<0.05) packed cell volume, erythrocyte count and higher (P<0.01) mean cell volumes than uninfected animals. Leucocytosis, reticulocytosis and thrombocytopenia were also observed. The infection also produced a decrease in albumin (P<0.001), significant increase in total protein and bilirubin levels. These changes were not seen in the animals that were not infected. The outcome of the work shows that herds are severely affected by the disease, and therefore supports the prospect of routine check as an epidemiologic tool in trypanosomiasis based on its abnormal effects in blood. Copyright © 2011 Elsevier B.V. All rights reserved. This article was published in Vet Parasitol and referenced in Journal of Clinical & Experimental Pharmacology

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