alexa Accuracy considerations in EPR dosimetry
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Journal of Proteomics & Bioinformatics

Author(s): Nagy V V

Abstract Share this page

Abstract A brief overview of some of the potential sources of inaccuracies that are common to all kinds of electron paramagnetic resonance (EPR) dosimetry is given. The instrumental sources discussed are inaccuracies of receiver gain calibration, instability of the spectrometer sensitivity, and neglect of inhomogeneity of the fields in the resonators. The discussed sources of inaccuracies related to data processing are violations of basic assumptions of the used version of the least-squares technique, incorrect model selection for fitting the data, and nonoptimal design of the calibration experiment. Methods for detecting and correcting such inaccuracies are briefly discussed and references to the original literature are given.
This article was published in Appl Radiat Isot and referenced in Journal of Proteomics & Bioinformatics

Relevant Expert PPTs

Relevant Speaker PPTs

  • Kun Yin
    Make Your Immunology Research Easy
    PPT Version | PDF Version
  • Anjana Rajput
    Conservation of superior phenotypes of teak (Tectona grandis) in central India
    PPT Version | PDF Version
  • Soha S M Mostafa
    Phycoremediation of olive mill wastewater (OMW) using cyanobacteria for sustainable bio fertilizer and biofuel production
    PPT Version | PDF Version
  • M V Raghavendra Rao
    Medical research – Scorpion as model
    PPT Version | PDF Version
  • A K Sreekala
    Floral structure in relation to pollination and breeding system of selected endemic Impatiens of Western Ghats
    PPT Version | PDF Version
  • Dwi Astuti
    Phylogenetic position of Psittacula parakeet bird from Enggano Island, Indonesia based on analyses of cytochrome b gene sequences
    PPT Version | PDF Version
  • Manche Santoshi Kumari
    Prevalence of otological disorders in diabetic patients with hearing loss
    PPT Version | PDF Version
  • Chol-Bum ‘Mike’ Kweon
    Chol-Bum-Mike-Kweon-US-Army-Research-Laboratory-USA-Unmanned-Aerial-System-(UAS)-engine-research-at-US-Army-research-laboratory
    PPT Version | PDF Version
  • S. R. Gollahalli
    S-R-Gollahalli-University-of-Oklahoma-USA-An-integrative-research-program-of-bio-fuel-combustion-performance-and-emissions
    PPT Version | PDF Version
  • Saroj Velamakanni
    Multiparameter analysis using cell cycle biomarkers for breast cancer: Prognostic and predictive implications
    PPT Version | PDF Version
  • Hazel Gorham
    Challenges in demonstrating biosimilarity and interchangeability of biosimilar products
    PPT Version | PDF Version
  • Francis Jeshira Reynoso
    The clinical phenotype of PIGN deficiency and consequences of defective GPI biogenesis
    PPT Version | PDF Version
  • Wang Bin
    Wang-Bin-Nanjing-University-of-Aeronautics-and-Astronautics-China-Simulation-research-of-driving-schemes-for-a-dynamic-calibration-system-of-fuel-turbine-flow-meters
    PPT Version | PDF Version
  • Yosef Yarden
    Classically, the 3’untranslated region (3’UTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3’UTR alone, without all other elements in mRNA such as 5’UTR and coding region. The importance of independent 3’UTR RNA (referred as I3’UTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3’UTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3’UTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3’UTR were important for its tumor suppression activity. Then, the C/EBP 3’UTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3’UTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3’UTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990’s to 2000’s, world scientists found several 3’UTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3’UTR regions, although the existence of their transcribed products as independent 3’UTR RNAs is still to be confirmed. Our studies indicate that the independent 3’UTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole.
    PPT Version | PDF Version
  • Lu Jia
    Lu-Jia-Taiyuan-University-of-Science-and-Technology-China-The-research-on-technological-parameters-of-short-forming-process-of-ring-parts
    PPT Version | PDF Version

Recommended Conferences

  • 9th International Conference on Bioinformatics
    October 23-24, 2017 Paris, France
  • 9th International Conference and Expo on Proteomics
    October 23-25, 2017 Paris, France

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords