alexa Activities of dalbavancin in vitro and in a rabbit model of experimental endocarditis due to Staphylococcus aureus with or without reduced susceptibility to vancomycin and teicoplanin.


Clinical Microbiology: Open Access

Author(s): Lefort A, Pavie J, Garry L, Chau F, Fantin B

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Abstract For the treatment of rabbit endocarditis, dalbavancin given once daily (10 mg/kg of body weight for 4 days) or as a single 40-mg/kg dose was active against Staphylococcus aureus with or without reduced susceptibility to glycopeptides, as expected from its good in vitro activity, even in broth supplemented with 90\% serum and given its prolonged elimination half-life.
This article was published in Antimicrob Agents Chemother and referenced in Clinical Microbiology: Open Access

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