alexa Adeno-associated virus vectors for gene therapy: more pros than cons?
Veterinary Sciences

Veterinary Sciences

Journal of Veterinary Science & Technology

Author(s): Monahan PE, Samulski RJ

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Abstract Gene therapy vectors based on the adeno-associated virus (AAV) are being developed for a widening variety of therapeutic applications. Enthusiasm for AAV is due, not only to the relative safety of these vectors, but also to advances in understanding of the unique biology of this virus. This review examines a number of long-standing concerns regarding the utility of AAV for gene transfer in light of many new insights into the biology, immunology and production of AAV.
This article was published in Mol Med Today and referenced in Journal of Veterinary Science & Technology

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